Temporal trends in ischemic stroke and anticoagulation therapy among Medicare patients with atrial fibrillation: a 15-year perspective (1992-2007).
نویسندگان
چکیده
A trial fibrillation (AF) is an independent, modifiable risk factor for ischemic stroke and independently associated with increased mortality. Nonvalvular AF is associated with a nearly 5-fold higher risk of ischemic stroke; this risk progressively increases with age. In a meta-analysis involving 29 clinical studies and 28 044 patients, judicious antithrombotic therapy with adjusted-dose warfarin was shown to
منابع مشابه
Atrial fibrillation and stroke in the general medicare population: a 10-year perspective (1992 to 2002).
BACKGROUND AND PURPOSE Clinical trials have illustrated warfarin's protective effect on stroke risk in patients with atrial fibrillation (AF). The current study investigated temporal trends in AF prevalence, warfarin use, and its relation to stroke risk in Medicare patients with AF from 1992 to 2002. METHODS The Medicare 5% sample for 1992 to 2002 was used to create 1-year cohorts of patients...
متن کاملAtrial Fibrillation, Stroke, and Anticoagulation in Medicare Beneficiaries: Trends by Age, Sex, and Race, 1992–2010
BACKGROUND We evaluated temporal trends in ischemic stroke and warfarin use among demographic subsets of the US Medicare population that are not well represented in randomized trials of warfarin for stroke prevention in nonvalvular atrial fibrillation (AF). METHODS AND RESULTS One-year cohorts of Medicare-primary payer patients (1992-2010) were created using the Medicare 5% sample. Internatio...
متن کاملAtrial Fibrillation and Stroke in the General Medicare Population
Background and Purpose—Clinical trials have illustrated warfarin’s protective effect on stroke risk in patients with atrial fibrillation (AF). The current study investigated temporal trends in AF prevalence, warfarin use, and its relation to stroke risk in Medicare patients with AF from 1992 to 2002. Methods—The Medicare 5% sample for 1992 to 2002 was used to create 1-year cohorts of patients w...
متن کاملCost efficiency of anticoagulation with warfarin to prevent stroke in medicare beneficiaries with nonvalvular atrial fibrillation.
BACKGROUND AND PURPOSE in controlled trials, anticoagulation with warfarin reduces stroke risk by nearly two thirds, but the benefit has been less pronounced in clinical practice. This report describes the extent of warfarin use, its effectiveness, and its impact on medical costs among Medicare patients with nonvalvular atrial fibrillation. METHODS using claims from >2 million beneficiaries i...
متن کاملEpidemiology and Prevention Trends in the Incidence of Atrial Fibrillation in Older Patients Initiating Dialysis in the United States
Background—One sixth of US dialysis patients 65 years of age have been diagnosed with atrial fibrillation/flutter (AF). Little is known, however, about the incidence of AF in this population. Methods and Results—We identified 258 605 older patients ( 67 years of age) with fee-for-service Medicare initiating dialysis in 1995 to 2007, who had not been diagnosed with AF within the previous 2 years...
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عنوان ژورنال:
- JAMA internal medicine
دوره 173 2 شماره
صفحات -
تاریخ انتشار 2013